Endocrine Abstracts

IntroductionMenopausal transition is associated with an increase in the cardiovascular risk, possibly related with the sharp decrease of estrogen levels. Menopausal symptoms and more specifically hot flushes have been previously linked with an increase in cardiovascular risk. On the other hand, non-alcoholic fatty liver disease is considered as another presentation of the metabolic syndrome, conferring additional cardiovascular risk to the affected indiv...

Introduction: Metabolic syndrome and cardiovascular disease (CVD) are well-known long-term implications of the menopausal transition. Lifestyle practices like exercise could potentially act protective with regards to future cardiovascular risk at midlife. We aimed to assess the impact of physical activity on the development of subclinical CVD in postmenopausal women, adjusting for the effect of underlying obesity.Methods: This cross-sectional study from ...

Background: Apart from traditional cardiovascular-risk factors and fluctuating sex hormone levels, environmental and lifestyle factors might also contribute to the heightened cardiovascular risk after menopause.Objective: To explore whether nutritional factors are associated with subclinical vessel disease in postmenopausal women.Methods: This cross-sectional study recruited 310 apparently healthy postmenopausal women, attending a ...

Background: Recent data is indicating that levels of circulating amyloid β 1-40 (αβ1-40), a proatherogenic aging peptide, may be considered as a novel biomarker in cardiovascular disease (CVD). Postmenopausal women represent a population with substantial unrecognized CVD-risk, which would benefit from identification of novel cardiovascular risk markers.Aim: To explore the role of plasma Aβ1-40 and its patterns of change over time in a...